granuloma parasitario de Koch

17:10 Jun 12, 2010 

...that thre is such a thing as a granuloma, but it's rare.

04:12 Jun 12, 2010 

I truly hope your husband's better now and I really mean that.

However, I feel that we are only here to help with a TRANSLATION. Perhaps on some other forum it would be more appropriate to discuss/explain what this illness, or any other, is all about. Kind regards, Muriel, and I meant what I said!

01:28 Jun 12, 2010 

My husband developed a granuloma under the conditions described below (http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis):
Mycobacterium outbreaks are often caused by hypervirulent strains of M. tuberculosis. In laboratory experiments, these clinical isolates elicit unusual immunopathology and may be either hyperinflammatory or hypoinflammatory. Studies have shown that the majority of hypervirulent mutants have deletions in their cell wall modifying enzymes or regulators that respond to environmental stimuli. Studies of these mutants have indicated the mechanisms that enable M. tuberculosis to mask its full pathogenic potential, inducing a granuloma that provides a protective niche and enables the bacilli to sustain a long-term persistent infection.

08:49 Jun 11, 2010 

But, hey, what do I know about medical translation? not much obviously.

08:47 Jun 11, 2010 

Medical translation is about understanding the terms, not just blindly translating what is in front of us.

08:36 Jun 11, 2010 

Thanks for your clarification, Dave, although I'm sure most of us understood this to be the case. However, I'm sure we've all learned anything we didn't already know about granulomas!

08:23 Jun 11, 2010 

Sorry if I wasn't clear. Only the translation of the words highlighted. Not the answer to the question.

06:57 Jun 11, 2010 

#
Granuloma formation and dissemination of Mycobacterium ...
by AGMAS Microbiol - 1999
Granuloma formation and dissemination of Mycobacterium tuberculosis: a novel role for B cells. Bosio CM, Elkins KL; American Society for Microbiology. ...
gateway.nlm.nih.gov/MeetingAbstracts/102195824.html - Cached - Similar
#
NEJM -- The Granuloma in Tuberculosis -- Friend or Foe?
by EJ Rubin - 2009 - Cited by 5 - Related articles
4 Jun 2009 ... On the one hand, activated macrophages are capable of killing or at least controlling the growth of M. tuberculosis. Granulomas are present ...
content.nejm.org/cgi/content/full/360/23/2471 - Similar

21:58 Jun 10, 2010 

Until a short time ago, that was also my impression. Hence, my answer.

21:52 Jun 10, 2010 

From what he wrote, my understanding is that Dave just wants a translation of the term in question. I think that it is very common on multiple-choice tests for many of the wrong answer choices to be made-up pseudo-entities that sound reasonable to an unprepared test-taker.

For support for my contention that (B) is the correct answer (which I admit is a tangential issue here), see http://www.aafp.org/afp/980415ap/moazzez.html.

21:50 Jun 10, 2010 

Well, perhaps Dave should clarify if he wants us to offer the right answer, or if he wants the translation of the question! If it's the latter, I think he should try another non-translation forum.

21:46 Jun 10, 2010 

I believe that the fact that this term cannot be found in any reference material or source whatsoever in Spanish (or English) is a key clue to how it should be translated in English. There is no such thing as "granuloma parasitario de Koch" (in English or Spanish; try Googling the phrase in both languages). I think that this is the point. This is an answer choice in a multiple-choice test, and it is obvious that the correct answer is not (A); it is probably (B).

Tuberculosis, which is the subject of the question, is also (less commonly) known as "Koch's disease" because a common form of tuberculosis is caused by "Koch's bacillus" (see http://www.encyclopedia.com/doc/1O62-Mycobacterium.html).

My best guess would be that the examiner is using that fact, which was perhaps presented in a class lecture or in the course reading, to confuse the unprepared test-taker with an answer choice that, on a superficial level, sounds plausible because it relies on terms that are somewhat familiar to the examinee.