disease-modifying anti-rheumatic drug (DMARD)

Turkish translation: hastalık modifiye edici antiromatizmal ilaçlar (DMARD)

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00:54 May 26, 2020
English to Turkish translations [PRO]
COVID-19 - Medical - Medical (general)
Additional field(s): Biology (-tech,-chem,micro-), Medical (general), Journalism
English term or phrase: disease-modifying anti-rheumatic drug (DMARD)
Definition from National Center for Biotechnology Info.:
Disease-modifying antirheumatic drugs (DMARDs) are a class of drugs indicated for the treatment of inflammatory arthritides including rheumatoid arthritis (RA), psoriatic arthritis (PsA), and ankylosing spondylitis (AS). They can also be used to in the treatment of other disorders including connective tissue disease such as systemic sclerosis (SSc), systemic lupus erythematosus (SLE), and Sjogren syndrome (SS), as well as in treatment of inflammatory myositis, vasculitis, uveitis, inflammatory bowel disease, and some types of cancers.

Example sentence(s):
  • Hydroxychloroquine has been available since 1955 as an antimalarial drug. I have at least 6 patients at the pharmacy who have used hydroxychloroquine to manage their rheumatoid arthritis, lupus, and Crohn disease. If you were sitting in my pharmacology class, I’d tell you that it is an antimalarial used as a disease-modifying antirheumatic drug (DMARD). I would tell you it is a cheap drug with good efficacy for some and also that it is 1 of 2 DMARDs that are safe to use in patients with liver failure. You would also learn that it may cause deposition of the drug in the melanin layer of the cones in the retina, underscoring the need for annual eye exams. MJH Life Sciences
  • DMARDs Not Linked to Poor Outcomes in SARS-CoV-2 RA Patients Rheumatology Network
  • The analysis of performance measures for rheumatoid arthritis (RA) care have allowed to identify gaps in care that include suboptimal use of disease-modifying anti-rheumatic drugs (DMARDs), according to a study published in Arthritis Care & Research. Rheumatology Advisor
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Turkish translation:hastalık modifiye edici antiromatizmal ilaçlar (DMARD)
Definition:
Romatoid artrit, psöriyatik artrit ve ankilozan spondilit gibi eklem iltihabı ile seyreden hastalıkların tedavisinde kullanılan; sıradan anti-inflamatuvar ve ağrı kesici ilaçların aksine etkileri daha yavaş ortaya çıkan, fakat inflamasyon sürecinin temel evrelerinde rol oynayarak eklem erozyonunu geciktirebilen ve bu sayede hastalığın seyrini değiştiren ilaçlardır. Tıbbi literatürde hemen daima "hastalık modifiye edici ilaçlar" olarak adlandırılırlar.
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Summary of translations provided
5 +2hastalık modifiye edici antiromatizmal ilaçlar (DMARD)
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1 hr   confidence: Answerer confidence 5/5 peer agreement (net): +2
hastalık modifiye edici antiromatizmal ilaçlar (DMARD)


Definition from own experience or research:
Romatoid artrit, psöriyatik artrit ve ankilozan spondilit gibi eklem iltihabı ile seyreden hastalıkların tedavisinde kullanılan; sıradan anti-inflamatuvar ve ağrı kesici ilaçların aksine etkileri daha yavaş ortaya çıkan, fakat inflamasyon sürecinin temel evrelerinde rol oynayarak eklem erozyonunu geciktirebilen ve bu sayede hastalığın seyrini değiştiren ilaçlardır. Tıbbi literatürde hemen daima "hastalık modifiye edici ilaçlar" olarak adlandırılırlar.

Example sentence(s):
  • Mevcut farmakolojik tedavi seçenekleri geleneksel sentetik hastalık modifiye edici antiromatizmal ilaçlar (csDMARD’lar), biyolojik DMARD’lar (bDMARD’lar) ve en yeni ilave olarak hedefe yönelik sentetik DMARD’ları (tsDMARD’lar) içermektedir. - Sağlık Bakanlığı  
  • 2010 kriterlerine göre, elde edilen veriler metotreksat (MTX) grubu için 0.804 duyarlılık (%95 güven aralığı [GA]; dağılım 0.737-0.857) ve 0.556 özgüllük (%95 GA; dağılım 0.417- 0.687); hastalık modifiye edici antiromatizmal ilaç (DMARD) grubunda 0.706 duyarlılık (%95 GA; dağılım 0.585-0.803) ve 0.691 özgüllük (%95 GA; dağılım 0.583-0.782) ve uzman grubunda 0.901 duyarlılık (%95 GA; dağılım 0.856-0.933) ve 0.539 özgüllük (%95 GA; dağılım 0.429-0.645) gösterdi. - TLAR  
  • DMARD ''Disease Modifying Anti-Rheumatic Drugs'' kelimelerinin kısaltmasıdır. Hastalığı modifiye eden anti-romatizmal ilaçlar demektir. Bu ilaçlar günümüzde RA yanında diğer inflamatuar hastalıklarda da yaygın olarak kullanılmaktadırlar. Bu ilaçlara DMARD yanında yavaş etkili ilaçlar, remisyon sağlayıcı ilaçlar, uzun etkili ilaçlar, temel tedavi ilaçları veya temel etkili ilaçlar da denmektedir. - turkiyeklinikleri  
FATİH ORUÇ
Türkiye
Local time: 11:36
Native speaker of: Native in TurkishTurkish
PRO pts in category: 172

Votes in favor of/against selecting this as the best translation of the term asked
Yes  Yeliz Melzer
10 days
  -> Teşekkürler Yeliz Hanım

Yes  Binnur Tuncel van Pomeren
10 days
  -> Teşekkürler Binnur Hanım
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