terminal prophylaxis
Russian translation: постконтактная профилактика
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| 20:30 Aug 19, 2020 |
| English to Russian translations [PRO] Medical - Medical (general) / Профилактика | |||||||
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|  Selected response from: Oleg Lozinskiy Russian Federation Local time: 17:13 | ||||||
Grading comment
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| Summary of answers provided | ||||
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| 4 | терминальная профилактика (или презумптивная протворецидивная терапия) |
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| 3 | постконтактная профилактика |
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Answers
12 mins confidence: 
постконтактная профилактика Explanation: * -------------------------------------------------- Note added at 14 мин (2020-08-19 20:45:55 GMT) -------------------------------------------------- Nasveld P, Kitchener S, Edstein M, Rieckmann K. Comparison of tafenoquine (WR238605) and primaquine in the post-exposure (terminal) prophylaxis of vivax malaria in Australian Defence Force personnel. Trans R Soc Trop Med Hyg 2002b;96:683-684. https://www.google.ru/url?sa=t&rct=j&q=&esrc=s&source=web&cd... -------------------------------------------------- Note added at 22 мин (2020-08-19 20:53:18 GMT) -------------------------------------------------- Primary Prophylaxis: Use of antimalaria drugs at recommended dosage, started 2-20 days before departure to a malarious area and continued for the duration of stay and for 1-4 weeks after return. Causal prophylaxis<//b>: This prevents the establishment of infection in the liver by inhibiting the pre-erythrocytic schizogony. Primaquine and proguanil are effective as causal prophylactic drugs. Potential adverse effects on long term use and non-availability of primaquine make it a difficult drug for this purpose. In one study in the Papua- New Guinea, it was found to be effective as a prophylactic agent. It is however not yet recommended for general use. Daily doses of proguanil provide causal prophylaxis in areas where resistance to this drug is not present. Suppressive prophylaxis: Use of blood schizonticides suppresses the blood forms of the malaria parasite and thus protects against clinical illness. However, P. vivax and P. ovale may cause relapses from the hypnozoites and to prevent this, terminal prophylaxis may be needed. [See below] Terminal Prophylaxis: Terminal prophylaxis is the administration of primaquine for two weeks after returning from travel to tackle the hypnozoites of P. vivax and P. ovale that can cause relapses of malaria. It is indicated only for persons who have had prolonged exposure in malaria-endemic regions, such as expatriates and long-term travelers like missionaries and Peace Corps volunteers. Primaquine is administered after the traveler leaves an endemic area and usually in conjunction with chloroquine during the last 2 weeks of the 4-week period of prophylaxis after exposure in an endemic area has ended. https://www.malariasite.com/prophylaxis/ -------------------------------------------------- Note added at 43 мин (2020-08-19 21:13:58 GMT) -------------------------------------------------- При этом термин "терминальная профилактика" применительно к малярии тоже употребляется (правда, согласно жесткому гугл-поиску всего в трех (3) случаях) --> https://www.google.ru/search?newwindow=1&biw=1045&bih=730&tb... |
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44 mins confidence:
терминальная профилактика (или презумптивная протворецидивная терапия) Explanation: профилактика во избежание вероятного/предполагаемого рецидива болезни -------------------------------------------------- Note added at 50 mins (2020-08-19 21:21:18 GMT) -------------------------------------------------- https://wwwnc.cdc.gov/travel/yellowbook/2020/travel-related-... In addition to primary prophylaxis, presumptive antirelapse therapy (also known as terminal prophylaxis) uses a medication toward the end of the exposure period (or immediately thereafter) to prevent relapses or delayed-onset clinical presentations of malaria caused by hypnozoites (dormant liver stages) of P. -------------------------------------------------- Note added at 56 mins (2020-08-19 21:27:41 GMT) -------------------------------------------------- https://www.google.com/search?q="терминальная профилактика"&... |
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