17:18 Jan 25, 2019 |
Chinese to English translations [PRO] Medical - Livestock / Animal Husbandry | |||||||
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| Selected response from: Gareth Callagy United Kingdom Local time: 10:13 | ||||||
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Summary of answers provided | ||||
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5 +1 | in its original form |
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4 +1 | unmetabolized |
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4 | prototype |
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4 | (as) parent (drug) |
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in its original form Explanation: in its original form |
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prototype Explanation: FYI |
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(as) parent (drug) Explanation: or: (excreted) unchanged 大鼠静脉注射八宝素36mg/kg后从尿、粪和胆汁(0~48h)中排泄的原型药物分别占给药总量的88.45%,0.61%和1·08%; http://www.cnki.com.cn/Article/CJFDTotal-DSDX200621022.htm After a single intravenous dose of 36 mg/kg Hylotelephin in rats, the excretion of the parent drug in urine, feces and bile amounted to 88.45%, 0.61% and 1.08% of the dose, respectively. http://en.cnki.com.cn/Article_en/CJFDTOTAL-DSDX200621022.htm |
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unmetabolized Explanation: ...excreted intact /unmetabolized/in (its) unmetabolized form However, some drugs, such as aminoglycoside antibiotics are polar compounds and are excreted by the kidneys without being metabolised first https://www.nottingham.ac.uk/nmp/sonet/rlos/bioproc/kidneydr... It is estimated that 75% to 90% of antibiotics used in food animals are excreted, largely unmetabolized, into the https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3194830/ note: some drugs are excreted/ eliminated in unmetabolized form, as the original drug molecule (e.g. Lithium) . http://psych.fullerton.edu/mwhite/475pdf/475pharmacokinetics... the increase in antibiotic resistant bacteria.7 Once consumed, most antibiotic drugs are excreted unmetabolized, ... https://wedocs.unep.org/bitstream/handle/20.500.11822/22263/... Intact and unmetabolized anthocyanins were detected in urine of rats and .... Thus, in vivo studies, either in animal and human assays, share the https://www.forbes.com/sites/quora/2018/02/16/how-do-antibio... Worse, since antibiotics are often excreted intact, low concentrations of antibiotics are |
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