gene deletion

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00:55 Mar 3, 2021

English to Chinese translations [PRO]
Medical - Medical (general)
Additional field(s): Biology (-tech,-chem,micro-), Medical: Pharmaceuticals, Genetics

English term or phrase: gene deletion

Definition from National Cancer :
The loss of all or a part of a gene. There may also be a change in the RNA and protein made from that gene. Certain gene deletions are found in cancer and in other genetic diseases and abnormalities.

Example sentence(s):

Gene deletions can also be applied in many different plant and human pathogenic fungi in order to decrease their pathogenicity and/or virulence for different applications. ScienceDirect
It is notable that targeted gene deletions generated via CRISPR/Cas9 and two guide RNAs resulted in the formation of correct junctions at high efficiency. Future Science
In the genomics era there is great demand for fast, simple high-throughput methods for gene deletion to study the roles of the large numbers of genes that are being identified. PubMed

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5 +1

基因缺失

Frank Feng

Discussion entries: 1

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1 hr confidence:

peer agreement (net): +1

基因缺失

Definition from genetics.cas.cn:
在遗传学中，基因缺失是一种基因突变，是指其中染色体的一部分或DNA序列在DNA复制过程中丢失。

Example sentence(s):

目的:检测肝癌患者血浆中p53基因突变和细胞核中p16基因缺失的机率,研究与疾病发生、发展的相关性并探讨其意义.方法:实验采用聚合酶联链式反应(PCR)扩增p53基因外显子5～8和免疫组织化学方法SP-p16,对其突变和缺失进行分析.结合临床患者有无肝组织以外转移来对比差异性 - alljournals.cn
目的探讨基因缺失发生于抗肌萎缩蛋白棒状结构区的Becker型肌营养不良症(Becker muscular dystrophy, BMD)的临床特征。 - 中华医学遗传杂志

Frank Feng
China
Local time: 12:13
Native speaker of: Chinese
PRO pts in category: 111

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