downstream processing

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00:55 Sep 23, 2020

English to Chinese translations [PRO]
Science - Medical: Pharmaceuticals
Additional field(s): Biology (-tech,-chem,micro-), Medical: Pharmaceuticals, Medical (general)

English term or phrase: downstream processing

Definition from Pharma IQ:
Downstream Processing refers to the recovery and purification of biosynthetic products, particularly pharmaceuticals, from natural sources such as animal or plant tissue or fermentation broth, including the recycling of salvageable components and the proper treatment and disposal of waste. It is an essential step in the manufacture of pharmaceuticals such as antibiotics, hormones (e.g. insulin and human growth hormone), antibodies (e.g. infliximab and abciximab) and vaccines; antibodies and enzymes used in diagnostics; industrial enzymes; and natural fragrance and flavor compounds. Downstream processing is usually considered a specialized field in biochemical engineering.

Example sentence(s):

Downstream processing can also impact the distribution and levels of product-related impurities. Accurate monitoring of product-related impurities, including higher molecular weight and lower molecular weight species is critical for product safety. Science Direct
EasyMax chemical reactor is for fundamental parameter optimization in downstream processing method design and execution. METTLER TOLEDO
Furthermore, because chromatography can represent a significant portion of the cost of goods in downstream processing (DSP) operations, proper optimization of capacity and selectivity is required. BioPharm

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Summary of translations provided

5 +1

下游加工

Yining Wang

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下游加工

Definition from 《药物生物技术》2003年第5期:
“下游加工过程包括目标产物的提取、浓缩、纯化及成品化过程。”

Example sentence(s):

“下游加工过程所应用的分离纯化技术取决于产物所在的位置及产物分子的大小、疏水性、电荷形式和溶解度等。” - 《药物生物技术》2003年第5期
“白细胞介素2的生产和下游加工过程” - 《药物生物技术》2003年05期
Understanding the rules of gene expression is required to make strategies for optimization of recombinant protein production in plants. The level of recombinant protein accumulation is important, but other factors such as plant selection ,processing of transgenic plant material, and downstream processing are equally important. 在研究和选择转基因植物表达系统的过程中 ,转化 ,转化后 ,翻译 ,翻译后等环节都会影响到最终产物的数量和质量 ,因此应该了解基因表达的规律 ,以制定植物生产重组蛋白合适的策略 ,重组蛋白积累水平是关键 ,但其它因素如植物的选择 ,转基因植物的处理 ,下游加工等同样重要 . - 《生物技术通讯》2004年02期

Yining Wang
United States
Local time: 19:04
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