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vitamin k-dependent plasma glycoprotein

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00:54 May 17, 2020
English to Czech translations [PRO]
COVID-19 - Science - Medical (general)
Additional field(s): Biology (-tech,-chem,micro-), Medical (general), Journalism
English term or phrase: vitamin k-dependent plasma glycoprotein
Definition from Science Direct:
Vitamin K–dependent proteins, synthesized in the liver, play a central role in blood coagulation through either procoagulant or anticoagulant mechanisms. The vitamin K–dependent protein family includes the zymogen procoagulant factors VII, IX, X, and prothrombin, and the anticoagulants protein C, protein S, and protein Z

Example sentence(s):
  • This gene encodes a liver vitamin K-dependent glycoprotein that is synthesized in the liver and secreted into the plasma. The encoded protein plays a role in regulating blood coagulation by complexing with protein Z-dependent protease inhibitor to directly inhibit activated factor X at the phospholipid surface. National Center for Biotechnology Info.
  • Protein Z is a vitamin K-dependent glycoprotein isolated and characterized from human and bovine plasma. A cDNA coding for human protein Z has been obtained by the isolation of phage clones from a liver cDNA library and in vitro amplification of two other liver libraries. Research Gate
  • Four proteins active in blood coagulation have long been known to require vitamin K for their proper biosynthesis: factors II, VII, IX, and X. This paper describes the purification of a hitherto unrecognized vitamin K-dependent glycoprotein from bovine plasma. The biosynthesis of this protein is interfered with by the vitamin K antagonist Dicoumarol. The JBC
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GBK medical and pharma specialistsGBK medical and pharma specialists


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Summary of translations provided
4plazmatický glykoprotein závislý na vitaminu k
Lucie Stehlíková


  

Translations offered


31 days   confidence: Answerer confidence 4/5Answerer confidence 4/5
plazmatický glykoprotein závislý na vitaminu k


Definition from Koagulační faktory:
Jsou to glykoproteiny a řadí se mezi globuliny. Tvoří se v játrech, jejich syntéza je závislá na vitamínu K a jejich funkce na iontech vápníku.

Example sentence(s):
  • Koagulační faktory jsou plazmatické globuliny, glykoproteiny přirozeně přítomné v krevní plazmě. Tvoří se v játrech a jejich syntéza je závislá na vitamínu K. - wikipedia  
  • Protein C je antikoagulační glykoprotein závislý na vitamínu K, který se tvoří v játrech. - takeda  
  • Faktor IX (FIX) je přibližně 55kDa glycoprotein závislý na vitamínu K, který se účastní procesu koagulace. - diagnostica  
Lucie Stehlíková
Czech Republic
Local time: 14:49
Native speaker of: Native in CzechCzech
PRO pts in category: 8
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