gene silencing

For term searches and specialty glossaries, please try the new GBK glossaries
13:57 Feb 9, 2010
English to Danish translations [PRO]
Science - Biology (-tech,-chem,micro-)
Additional field(s): Medical (general), Genetics
English term or phrase: gene silencing
Definition from MedicineNet, Inc.:
Gene silencing: A mechanism by which cells shut down large sections of chromosomal DNA. Gene silencing is done by incorporating the DNA to be silenced into a form of DNA called heterochromatin that is already silent. The process of gene silencing is important for the differentiation of many different types of cells.

Example sentence(s):
  • Evidence is emerging that geminiviruses and plant pararetroviruses can interact with the gene silencing system either from introduced DNA constructs or during viral pathogenesis. Some observations suggest there are complex relationships between DNA viral activity, transcriptional and post-transcriptional gene silencing mechanisms. biotech-info.net
  • The biggest challenges in the field at the moment are understanding two things: how does DNA methylation participate in gene silencing (and that includes what molecules target the DNA methylation to these promoter regions), and why is the cancer cell doing this? The Thomson Corporation
  • In 2005, Pikaard and his collaborators published research showing that the major function of Pol IV is to generate siRNAs, thereby singling out this RNA polymerase as a potential player in gene silencing. ScienceDaily LLC
Glossary-building KudoZ




This question was created by:


This question will remain open until an answer receives the required level of agreement from peers. Submission is still possible.


Summary of translations provided
4 +1Gene silencing
Susmi Rosenthal


  

Translations offered


5 hrs   confidence: Answerer confidence 4/5Answerer confidence 4/5 peer agreement (net): +1
Gene silencing


Definition from Techmedia A/S:
Meget simplificeret fungerer gene silencing ved at små dobbeltstrengede RNA molekyler (20-30 nukleobaser i længde) forhindrer matchende mRNA sekvenser i at blive translateret, hvilket i sidste ende resulterer i at det kodende gen »slukkes«.

Example sentence(s):
  • Mens forskere og virksomheder forsøger at realisere antisense-drømmen har et nyt koncept, kendt som gene silencing,14 baseret på siRNA (small interfering RNA), trådt ind i rampelyset. Gene silencing blev i sin tid opdaget ved et tilfælde. - Techmedia A/S  
  • Resistens mod kartoffelskimmel gennem "gene silencing" rettet mod Phytophthora infestans. - Fødevareministeriet  
  • Medinova har en lang række produkter inden for RNAi / Gene Silencing som repræsenterer flere forskellige teknikker. ... Short Hairpin RNA vektorer (shRNA) til gene silencing fra Origene. - Medinova Scientific A/S  
Susmi Rosenthal
Canada
Local time: 10:58
Native speaker of: Native in DanishDanish
PRO pts in category: 4

Votes in favor of/against selecting this as the best translation of the term asked
Yes  Ditte Gry Svensmark: There is currently no danish term, so "gene silencing" is correct.
708 days
Login to enter a peer comment (or grade)



Login or register (free and only takes a few minutes) to participate in this question.

You will also have access to many other tools and opportunities designed for those who have language-related jobs (or are passionate about them). Participation is free and the site has a strict confidentiality policy.

KudoZ™ translation help

The KudoZ network provides a framework for translators and others to assist each other with translations or explanations of terms and short phrases.


See also:
Term search
  • All of ProZ.com
  • Term search
  • Jobs
  • Forums
  • Multiple search