co-crystals

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00:55 Sep 4, 2020
English to German translations [PRO]
Medical - Medical (general)
Additional field(s): Medical: Pharmaceuticals, Medical: Health Care, Science (general)
English term or phrase: co-crystals
Definition from Pharma IQ:
Co-Crystals are defined as a technology used to enhance solubility, stability and the IP position with respect to the development of active pharmaceutical ingredients (APIs). Exploring the co-crystallization potential around an API increases the intellectual property protection over a particular drug product; thus, reducing the risk of costly litigation and market erosion.

Example sentence(s):
  • In addition space is not limited to binary combinations (acid-base pairs) since tertiary and quaternary co-crystals are realistic one Indian J Pharm Sci.
  • In addition, co-crystals of the muscle relaxant metaxalone have been reported to improve preclinical in vivo bioavailability. Dove Press
  • As part of an effort to clarify and help advance the development of pharmaceutical co-crystals, the US Food and Drug Administration (FDA) on Tuesday released revised draft guidance providing information on the appropriate classification of co-crystal solid-state forms, the data that should be submitted to support the classification and the regulatory implications of such a classification. Regulatory Focus™
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GBK medical and pharma specialistsGBK medical and pharma specialists


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Summary of translations provided
5 +1Co-Kristalle
Edith Kelly


  

Translations offered


3 hrs   confidence: Answerer confidence 5/5 peer agreement (net): +1
Co-Kristalle


Definition from Chemie Ingenieur Technik:
Co-Kristalle repräsentieren neue Strukturmodelle, die insbesondere in der Pharmaindustrie großes Interesse erfahren, da anstelle einer additiven Kombination der Eigenschaften der Komponenten eine überproportionale Wirkungssteigerung im Co-Kristall erzielt werden kann. Der Begriff Co-Kristall wird für ganz unterschiedliche Strukturen verwendet.

Example sentence(s):
  • In der frühen Phase der Arzneimittelentwicklung muss die Entscheidung getroffen werden, ob das ungeladene Molekül als Wirkstoff geeignet ist. Wenn es ungeeignet ist, beispielsweise aufgrund geringer Löslichkeit, chemischer Stabilität oder des niedrigen Schmelzpunkts, müssen andere Optionen wie Salze oder Co-Kristalle in Erwägung gezogen werden. - Solvias  
  • Pulverformulierung umfassend Imidacloprid und Oxalsäure, sowie Verfahren zur Herstellung von Co-Kristallen umfassend Imidacloprid und Oxalsäure durch Kompaktieren - FPO  
  • Schwerpunkte unserer Arbeitsgruppe liegen auf der kontrollierten Synthese pharmazeutischer Co-Kristalle und Untersuchungen der Polymorphie- und Aggregationsphänomenen im Festkörper. Eine wichtige Rolle spielen dabei Wasserstoffbrücken- und Halogenbindungen, sowie H/D-Austausch - hhu  

Explanation:
Ko-Kristall wird auch manchmal verwendet.
Edith Kelly
Switzerland
Local time: 12:27
Native speaker of: Native in GermanGerman, Native in EnglishEnglish
PRO pts in category: 177
Notes to answerer
Agnes Schmidt Schreibung Ko-Kristalle


Votes in favor of/against selecting this as the best translation of the term asked
Yes  Agnes Schmidt: Ko-Kristall, gemischte Kristalle laut einem Artikel der Universität Innsbruck (https://www.uibk.ac.at/ipoint/news/2011/gemischte_kristalle....
1 day 2 hrs
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