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gene deletion

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00:54 Mar 3, 2021
English to Indonesian translations [PRO]
Medical - Medical (general)
Additional field(s): Biology (-tech,-chem,micro-), Medical: Pharmaceuticals, Genetics
English term or phrase: gene deletion
Definition from National Cancer :
The loss of all or a part of a gene. There may also be a change in the RNA and protein made from that gene. Certain gene deletions are found in cancer and in other genetic diseases and abnormalities.

Example sentence(s):
  • Gene deletions can also be applied in many different plant and human pathogenic fungi in order to decrease their pathogenicity and/or virulence for different applications. ScienceDirect
  • It is notable that targeted gene deletions generated via CRISPR/Cas9 and two guide RNAs resulted in the formation of correct junctions at high efficiency. Future Science
  • In the genomics era there is great demand for fast, simple high-throughput methods for gene deletion to study the roles of the large numbers of genes that are being identified. PubMed
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Question posted on behalf of translation team:
GBK medical and pharma specialistsGBK medical and pharma specialists


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Summary of translations provided
5delesi gen
Nur Shabrina


  

Translations offered


10 hrs   confidence: Answerer confidence 5/5
delesi gen


Definition from Campbell,N.A.,dkk.2008. Biologi.Jilid 1 :
Delesi gen adalah hilangnya satu atau lebih basa nitrogen dari segmen DNA. Mutasi ini berefek merusak pada protein yang dihasilkan. Delesi gen mungkin mengubah bingkai pembacaan pesan genetik, penggugusan triplet basa pada mRNA yang dibaca saat translasi.

Example sentence(s):
  • Beta-talasemia sebagian besar disebabkan oleh mutasi titik, insersi atau delesi dalam gen beta-globin yang terletak pada lengan pendek kromosom 11. - Jurnal Kedokteran Yarsi  
  • Tujuan dari penelitian ini adalah untuk mendeteksi adanya kejadian delesi dan mutasi pada gen Mx1 babi. - Jurnal Ilmu Ternak dan Veteriner  
  • Sekuen DNA yang diperoleh dari masing-masing individu yang dikaji dan sekuen DNA spesies yang diperoleh dari data bases internasional DDBJ (DNA Data Bank of Japan) (Tabel. 1) digunakan sebagai dasar untuk mengetahui proporsi insersi dan delesi gen RDP1 nukleus - Jurnal Biologi Edukasi  

Explanation:
Saya menyunting sedikit informasi mengenai definisi delesi gen dari Wikipedia yang mensitasi Campbell. Kalimat pertama definisi tersebut saya ambil dari https://www.zenius.net/prologmateri/biologi/a/1275/mutasi_dn...

Terima kasih.
Nur Shabrina
Indonesia
Native speaker of: Native in IndonesianIndonesian
PRO pts in category: 4
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