reduce ~ of all four tested drugs by a factor of 3-30 fold

Japanese translation: 3から30倍だけ低下させることができる

GLOSSARY ENTRY (DERIVED FROM QUESTION BELOW)

English term or phrase:	reduce ~ of all four tested drugs by a factor of 3-30 fold
Japanese translation:	3から30倍だけ低下させることができる
Entered by:	Yasutomo Kanazawa

13:18 Dec 31, 2009

English to Japanese translations [PRO]
Medical - Mathematics & Statistics

English term or phrase: reduce ~ of all four tested drugs by a factor of 3-30 fold

Wishing you all A Happy New Year, this is my last question in 2009
( I am in GMT +10 country)
The context:
the Puc19 DNA vector transfection is necessary for reaching the efficacy effect for the triple combination. Combination of Puc19 trasnfection with chemotherapy drugs could reduce the IC50 of all four tested chemotherapy drugs (paclictaxel, Doxourubicin, Cis-platinum, and 5-FU) ＊by a factor of 3-30 fold＊.

どう訳せばいいでしょうか、よろしくお頼みもうしあげます。

Yumico Tanaka (X) KudoZ activity Questions: 180 (none open) (8 without valid answers) (12 closed without grading) Answers: 334 Australia
Local time: 20:54

下記参照。

Explanation:
reduce the IC50 of all four tested chemotherapy drugs (paclictaxel, Doxourubicin, Cis-platinum, and 5-FU) ＊by a factor of 3-30 fold＊.
全て4つの試された化学療法薬(paclictaxel, Doxourubicin, Cis-platinum, and 5-FU)のIC50を3から30倍だけ減らすことができる、という訳になると思います。

by a factor ofは成形句で「倍だけ」と言う意味です。

http://dic.yahoo.co.jp/dsearch?enc=UTF-8&p=factor&stype=0&dt...

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Note added at 1 hr (2009-12-31 14:39:17 GMT)
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ここでのfoldの意味は「倍の」という意味です。例としては、threeーfold increaseというと3倍増という意味です。

Selected response from:

Yasutomo Kanazawa
Japan
Local time: 19:54

Grading comment

Thanks you.
4 KudoZ points were awarded for this answer

Summary of answers provided

下記参照。

Yasutomo Kanazawa

Summary of reference entries provided

FYR

cinefil

Answers

12 mins confidence:

下記参照。

Yasutomo Kanazawa
Japan
Local time: 19:54
Native speaker of:

Japanese
PRO pts in category: 20

Grading comment

Thanks you.

Notes to answerer

Asker: あけましておめでとうございます。そうですよね、でもこのfoldが気になってるんですが、同じことでしょうか。

Asker: ご協力いただき、ありがとうございます。これは｢減らす」ではなく｢低下する」を使うということがわかりましたので、terminologyよろしくお願いします。

Reference comments

53 mins

Reference: FYR

Reference information:
by a factor of
〜ばいで［〜倍で］
数字を伴って「（増減の規模が）〜倍で」という意味。このfactorは数学における因数分解の「因数」の意。
E-DIC

http://www.honyakunoizumi.info/class/Class_018.htm
http://ir.kyowa-kirin.co.jp/pdf/report-090323.pdf

foldが気になりますね。3-30 foldで一つの言葉なんでしょうか？
だとすると3-30 foldの倍減らす？

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Note added at 1時間 (2009-12-31 14:26:53 GMT)
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多分タンパク質の折り畳みに関係があるのでは？

cinefil
Japan
Native speaker of:

Japanese
PRO pts in category: 23

Note to reference poster

Asker: そうなんです、このfoldがわからないんです。。今こちらでは花火がおわりました、2010年です。あけましておめでとうございます。

Asker: proteinの折りたたみ、なるほど。。。！ありがとうございます。

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reduce ~ of all four tested drugs by a factor of 3-30 fold

Japanese translation: 3から30倍だけ低下させることができる

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reduce ~ of all four tested drugs by a factor of 3-30 fold

Japanese translation: 3から30倍だけ低下させることができる

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