Antibodies to L-PAM-tumor protein complexes

Spanish translation: anticuerpos dirigidos contra complejos entre proteínas tumorales y L-PAM

GLOSSARY ENTRY (DERIVED FROM QUESTION BELOW)
English term or phrase:Antibodies to L-PAM-tumor protein complexes
Spanish translation:anticuerpos dirigidos contra complejos entre proteínas tumorales y L-PAM
Entered by: Yvonne Becker

03:37 Jan 27, 2016
English to Spanish translations [PRO]
Medical - Biology (-tech,-chem,micro-)
English term or phrase: Antibodies to L-PAM-tumor protein complexes
Estoy traduciendo un estudio titulado "Hypersensitivity Reactions to i.v. Melphalan during Treatment of Multiple Myeloma: Cancer and Leukemia Group B Experience".

"The mechanism responsible for the hypersensitivity reactions in these patients is unknown. It has been shown previously that an alkylation reaction between L-PAM and serum proteins may occur in vivo (7) and that such altered proteins may serve as new antigens capable of stimulating antibodies to the hapten-protein complex (8). **Antibodies to L-PAM-tumor protein complexes** have been shown to cause tumor regression in certain animals, provided the tumor has been pretreated with L-PAM (9). It is thus conceivable that antibodies to L-PAM-cellular protein complexes could play a role in the damage myeloma or normal cells and that the release of such complexes from such damaged cells could initiate a hypersensitivity reaction under certain circumstances."

L-PAM = melfalán

Un millón de gracias por sus sugerencias
Yvonne Becker
Local time: 15:32
anticuerpos dirigidos contra complejos entre proteínas tumorales y L-PAM
Explanation:
saludos
Selected response from:

Teresa Mozo
Local time: 20:32
Grading comment
Muchísimas gracias, Teresa
4 KudoZ points were awarded for this answer



Summary of answers provided
4 +1anticuerpos dirigidos contra complejos entre proteínas tumorales y L-PAM
Teresa Mozo


  

Answers


2 hrs   confidence: Answerer confidence 4/5Answerer confidence 4/5 peer agreement (net): +1
antibodies to l-pam-tumor protein complexes
anticuerpos dirigidos contra complejos entre proteínas tumorales y L-PAM


Explanation:
saludos

Teresa Mozo
Local time: 20:32
Specializes in field
Native speaker of: Native in SpanishSpanish
PRO pts in category: 255
Grading comment
Muchísimas gracias, Teresa

Peer comments on this answer (and responses from the answerer)
agree  Gerardo Lin
12 hrs
  -> muchas gracias
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