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distanze genetiche a catena

English translation: genetic linkage distances

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Italian term or phrase:distanze genetiche a catena
English translation:genetic linkage distances
Entered by: achisholm

20:56 Jan 7, 2011
Italian to English translations [PRO]
Science - Genetics / animal genotyping
Italian term or phrase: distanze genetiche a catena
This is from an article describing a protocol for genotyping farm animals (based on microsatellite analysis and computer analysis if the alleles detected by PCR).

"La generazione di distanze genetiche a catena (Chord distance DAS, shared allele distance)17, tra gli allevamenti è stata determinata con l’uso del software POPULATIONS 1.2.3018. Tali distanze sono state usate per la costruzione di alberi filogenetici (neighbor-joining tree) mediante il software PHYLIP 3.519, visualizzati attraverso M-S Windows Bitmap file.bpm"
achisholm
United Kingdom
Local time: 22:40
genetic distances
Explanation:
This can be subdivided into different categories, such as "minimum genetic distance", and others such as DAS, etc.

http://bioinformatics.org/~tryphon/populations/

--------------------------------------------------
Note added at 14 mins (2011-01-07 21:10:25 GMT)
--------------------------------------------------

DAS = shared allele distances
Ds = standard genetic distance
etc.

http://bioinformatics.org/~tryphon/populations/formules/das....

--------------------------------------------------
Note added at 16 mins (2011-01-07 21:12:38 GMT)
--------------------------------------------------

These refer to distances on the DNA chain (hence the use of "catena".)
How far the alleles are from each other. The closer they are, the more the chances that they will not be "segregated", and that they will move together into next generation members. For example, if the gene for blue eye and small nose are very close, then one would expect the blue eye trait to appear with the small nose trait in many of the offspring members.

--------------------------------------------------
Note added at 19 mins (2011-01-07 21:15:30 GMT)
--------------------------------------------------

one reason for all members of a progeny not being identical is that the chromosomes undergo a "cross-over" as a result of which genes and alleles are scrambled. But if two genes are very close to each other, chances are they will move together, like a mother or father holding a child's hand and walking together....
Selected response from:

Zareh Darakjian Ph.D.
United States
Local time: 14:40
Grading comment
Many thanks.
4 KudoZ points were awarded for this answer



Summary of answers provided
4genetic distances
Zareh Darakjian Ph.D.


  

Answers


12 mins   confidence: Answerer confidence 4/5Answerer confidence 4/5
genetic distances


Explanation:
This can be subdivided into different categories, such as "minimum genetic distance", and others such as DAS, etc.

http://bioinformatics.org/~tryphon/populations/

--------------------------------------------------
Note added at 14 mins (2011-01-07 21:10:25 GMT)
--------------------------------------------------

DAS = shared allele distances
Ds = standard genetic distance
etc.

http://bioinformatics.org/~tryphon/populations/formules/das....

--------------------------------------------------
Note added at 16 mins (2011-01-07 21:12:38 GMT)
--------------------------------------------------

These refer to distances on the DNA chain (hence the use of "catena".)
How far the alleles are from each other. The closer they are, the more the chances that they will not be "segregated", and that they will move together into next generation members. For example, if the gene for blue eye and small nose are very close, then one would expect the blue eye trait to appear with the small nose trait in many of the offspring members.

--------------------------------------------------
Note added at 19 mins (2011-01-07 21:15:30 GMT)
--------------------------------------------------

one reason for all members of a progeny not being identical is that the chromosomes undergo a "cross-over" as a result of which genes and alleles are scrambled. But if two genes are very close to each other, chances are they will move together, like a mother or father holding a child's hand and walking together....

Zareh Darakjian Ph.D.
United States
Local time: 14:40
Specializes in field
Native speaker of: Native in EnglishEnglish, Native in ArmenianArmenian
PRO pts in category: 4
Grading comment
Many thanks.
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