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Sintesi dell’intermedio amminoesilico

English translation: synthhesis of aminohexyl[-ASO] intermediate

15:47 Nov 12, 2020
Italian to English translations [PRO]
Medical - Medical (general) / clinical trial
Italian term or phrase: Sintesi dell’intermedio amminoesilico
Qualità

3. S.2.2 _ Sintesi dell’intermedio amminoesilico, Figura 3: UnyLinker è riportato, dopo il primo passaggio (a) e fino in fondo
alla sintesi, prima del distacco dalla resina, come legato alla resina stessa con un gruppo CH2X invece che COX. Si richiede
di chiarire e correggere ove necessario.
4. S.2.2 _ Si richiede di riportare la sintesi del THA-PFP cluster.

5. S.2.3 _ Si richiede di stabilire un limite per la purezza dello starting material THA PFP Ester (MS-00910).

6. S.2.6 _ La dicitura “not applicable” non è accettabile. Si richiede di compilare la sezione secondo quelle che sono le
indicazioni fornite dalla linea guida EMA/CHMP/QWP/545525/2017

7. S.3.2 _ Si richiede di fornire un razionale per la non inclusione in sezione S.3.2 delle seguenti classi di impurezze: DMTphosphonate monoesters; DMT-phosphonate diesters; Ethylene phosphorothioate diester (EPD); Ethylene
phosphorodithioate diester; Ethylene(diisopropylamino)thioate diester; 1,4-anhydro-2-deoxy-D-erythro-pent-1-enitol
abasic.
garrett higgins
Local time: 22:18
English translation:synthhesis of aminohexyl[-ASO] intermediate
Explanation:
Not sure about this, though.

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Note added at 18 mins (2020-11-12 16:06:10 GMT)
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sorry, typo: synthesis
Selected response from:

Lirka
Austria
Local time: 23:18
Grading comment
thanks
4 KudoZ points were awarded for this answer



Summary of answers provided
2synthhesis of aminohexyl[-ASO] intermediate
Lirka


Discussion entries: 4





  

Answers


18 mins   confidence: Answerer confidence 2/5Answerer confidence 2/5
synthhesis of aminohexyl[-ASO] intermediate


Explanation:
Not sure about this, though.

--------------------------------------------------
Note added at 18 mins (2020-11-12 16:06:10 GMT)
--------------------------------------------------

sorry, typo: synthesis

Lirka
Austria
Local time: 23:18
Specializes in field
Native speaker of: Native in EnglishEnglish
PRO pts in category: 572
Grading comment
thanks
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