Граница клинически незначимого различия
English translation: boundary of clinically negligible difference
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| 10:19 Aug 18, 2020 |
| Russian to English translations [PRO] Science - Medical: Pharmaceuticals / Clinical trials | |||||||
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|  Selected response from: Michael Sarni United Kingdom Local time: 23:49 | ||||||
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| 3 | boundary of clinically negligible difference |
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| 3 | clinically insignificant difference limit/boundary |
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Answers
19 mins confidence: 
boundary of clinically negligible difference Explanation: вариант: limit |
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1 hr confidence:
clinically insignificant difference limit/boundary Explanation: Результаты Частота ответа ASAS20 на 16-й неделе в группе НТК составила 72,73% (95%-ный ДИ [1,69%; 58,05%]), 81,82% (95%-ный ДИ [12,36%; 65,56%]) и 90,91% (95%-ный ДИ [23,71%; 72,39%]) для доз 40, 80 и 120 мг. Частота ответа в группе плацебо составила 42,86%. Предустановленный протоколом исследования предел клинически незначимого различия составил 10%. Было подтверждено превосходство в клинической эффективности для доз препарата 80 и 120 мг по сравнению с плацебо. Наиболее распространенные нежелательные явления (НЯ) включали лимфоцитоз, нейтропению и бессимптомную бактериурию. Случаев дозозависимой токсичности или серьезных нежелательных явлений (СНЯ) зарегистрировано не было. Доза НТК 120 мг была признана наиболее эффективной с самым быстрым началом действия и благоприятным профилем безопасности. https://efleira.ru/wp-content/uploads/2020/04/Erdes_preview_... There was a clinically insignificant difference in the calf minus toe temperature index between the saline and su- fentanil groups https://watermark.silverchair.com/0000542-199807000-00013.pd... Results There was a statistically significant but clinically insignificant difference in operating time and intraoperative blood loss in favor of the traditional https://jamanetwork.com/journals/jamaotolaryngology/fullarti... |
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