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English to Croatian: Mehanizam i potencijal liječenja raka retinoidima General field: Medical Detailed field: Medical (general)
Source text - English ''Cross-talk'' of Nuclear Receptors with Other Signaling Pathways
Nucelar receptors can also modulate gene expression by mechanisms independent of binding to an HRE. Thus, they can alter expressions of genes that do not contain a HRE through positive or negative interference with the activity of other transcription factors, a mechanism generally referred to as ''transcriptional cross-talk''. Thus, the receptors can negatively regulate target gene promoters that carry AP1, NFkB, or CREB-binding sites, without binding to these DNA elements themselves. The mechanisms responsible are not totally understood and can involve direct protein-to-protein interaction of the receptors with these transcription factors, or with intermediary factors that tether the receptors to the regulated promoter. The receptors can also regulate the activity of the signaling pathways that lead to the activation of these factors by different mechanisms. It is believed that many of the antiproliferative effects and anti-inflamatory actions of ligands of nuclear receptors could be mediated by ''cross-talk'' mechanisms.
Translation - Croatian Cross – talk jezgrenih receptora s ostalim signalnim putevima
Jezgreni receptori također mogu modulitari gensku ekspresiju uz pomoć mehanizama koji ne ovise o vezanju za HRE. Prema tome, mogu mijenjati ekspresiju gena koji ne sadržavaju HRE preko pozitivnog ili negativog miješanje s aktivnošću nekih drugih transkripcijskih faktora, mehanizmom nazvanim transkripcijskim cross- talkom. Prema tome, receptori mogu negativno regulirati ciljne promotore gena koji nose AP1, NgkapaB, ili CRED vezana mjesta, a da ne vežu i sami za te elemente DNK-a. Mehanizmi koji to potiču još uvijek nije potpuno shvaćeni te mogu uključivati izravnu interakciju protein-protein receptora s tim transkripcijkim faktorima ili s intermedijarnim faktorma koji vežu receptore s regulatornim promotorima. Receptori mogu također regulirati aktivnost signalnih puteva koji vode aktivaciji tih faktora, ali drugim mehanizmima. Smatra se da mnogi antiproliferativni učinci i protuupalna aktivnost liganada nuklearnih receptora mogu biti posredovani cross-talk mehanizmima.
Croatian to English: Forest park Kunjevci, significant landscape Spačva, Bapska – church, Cerna – church, Nuštar – Khuen-Belany castle, Lipovac – church, Novi Mikanovci – church, Šarengrad – Medieval fortification General field: Other Detailed field: Tourism & Travel
Source text - Croatian Spačva – najveća cjelovita šuma hrasta lužnjaka u Hrvatskoj
"Kad kažem hrast, mislim na spačvanske šume", napisao je književnik i šumar Josip Kozarac 1888. godine.
U međuriječju Save i Dunava nalazi se najveća cjelovita šuma hrasta lužnjaka Spačva. Pokriva površinu od 40.000 hektara, a širi spačvanski bazen je veći i iznosi približno 51.000 hektara. I u Europi Spačva pripada među najveće cjelovite hrastove šume. Glavne su vrste drveća u Spačvi: hrast lužnjak, poljski jasen, nizinski brijest, obični grab i klen. U Spačvi je hrast lužnjak dobio zbog svoje odlične kakvoće međunarodnu tehnološku karakteristiku pod imenom slavonska hrastovina. O veličini i važnosti hrastovih šuma promatranog područja svjedoči podatak da se jedna petina svih lužnjakovih šuma u Hrvatskoj nalazi se upravo u Spačvi. Za razliku od vrlo starih hrastova golemih dimenzija i velike starosti, sadašnje spačvanske šume imaju većim dijelom oko 80 do 120 godina, a srednji im je prsten promjera oko 40 do 60 cm. Kada šume dožive 140 godina smatraju se zrelima, a Marija Terezija je smatrala svojom uredbom da treba proći 200 godina pa da se pristupi sječi. Sadašnji Pravilnik o uređivanju šuma predviđa 140 godina kao minimalnu ophodnju za hrast lužnjak.
Od drva hrasta lužnjaka iz Hrvatske diljem Europe izrađeni su crkveni krovovi, vrata, prozori. U Budimpešti je izgrađen neogotički parlament, te vrata i prozori u Muzeju povijesti umjetnosti. Mnoge ustanove u Beču (neogotička građevina Nove vijećnice, palače i dr.) imaju drvenu opremu izrađenu od slavonske hrastovine.
Translation - English Spačva – the largest intact English oak forest landscape in Croatia
“When I say oak, I mean Spačva Forest”, Josip Kozarac wrote, an author and a forester. Between the rivers Sava and Dunav the largest intact English Oak forest landscape Spačva is located. It covers the area of 40,000 hectares, and the broader Spačvan pool is approximately 51,000 ha in size. Spačva is one of the biggest intact oak tree forests in Europe. Its most common tree types are: English oak, narrow-leafed ash, field elm, common hornbeam and field maple. English oak in Spačva got an international technological characteristic under the name of Slavonian oak due to its excellent quality. One fifth of all English oak forests in Croatia are located in Spačva, which signifies its size and importance. Forests of Spačva do not have big and old oaks; their average age is between 80 and 120 years with a medium trunk diameter of 40-60 cm. Forests are considered mature with an age of 140 years and in pursuant to Maria Theresa’s directive, 200 years were supposed to pass before cutting. Ordinance on forest management proclaims a minimum of 140 years have to pass before the cutting cycle.
Oak wood from Croatia was used as construction material in Europe for church roofs, doors, windows… A Neo-gothic style parliament house was built in Budapest, and the doors and windows of the Museum of Art History. Many of the Vienna’s establishments (Neo-gothic New city hall, palaces, etc.) have wooden parts made of Slavonian oak.
Croatian to English: Semeljci Primary School (Summary) General field: Social Sciences Detailed field: Other
Source text - Croatian Semeljačko područje bilo je naseljeno već u neolitu. Semeljci su selo smješteni u Slavoniji, u istočnom dijelu Đakovštine.
Škola u Semeljcima otvorena je 1786.godine. Nakon osnivanja borila se s raznim teškoćama. Josip Zadravec je prvi učitelj u Semeljcima. Prva školska zgrada je bila drvena, imala je školsku sobu, dvije sobe za učitelja i kuhinju. U školi se podučavao uz ilirski i njemački jezik. Druga školska zgrada sagrađena je do 1833.godine. Građena na brzinu i s malim sredstvima. Godine 1875. semeljačku školu polazili su samo dječaci. Tako se ova škola razvijala iz dvorazredne u potpunu četverorazrednu pučku školu.
U svibnju 1895.godine srušena je stara zgrada. Nova Opća pučka škola u Semeljcima otvorena je 27. listopada 1895. Polazilo je 240 učenika. 1951./52. odobreno je da se u Semeljcima otvori redovna osmogodišnja škola. U školskoj godini 1959/60. spajaju se sve do sada samostalne osnovne škole u jednu centralnu Osnovnu školu. U 9. mjesecu 1960. godine škola dobiva naziv Osnovna škola ,,Josip Kozarac“ Semeljci. Učenici do 4. razreda idu u školu u područnim odjeljenjima, a poslije završenog 4.razreda nastavljaju školu u matičnoj školi u Semeljcima. Iskop temelja nove školske zgrade započeo je u listopadu 1974.godine, a otvaranje je obavljeno 21. prosinca 1975.godine. Školska zgrada u Semeljcima građena je na dvije etape: 12 specijaliziranih učionica, radionica za tehnički odgoj, čitaonicu, kuhinju s blagavaonicom, dvoranu za tjelesni odgoj i sportski tereni.
Osnovna škola ,,Josip Kozarac“ Semeljci je matična škola koja je sadržavala, i još uvijek sadrži, pet područnih škola, a to su u Kešincima, Vrbici, Forkuševcima, Vučevcima i u Mrzoviću. Danas škola u Semeljcima ima 450 učenika i 50-ero prosvjetnih radnika.
Translation - English The locality of Semeljci was inhabited as early as the Neolithic Period. Semeljci is a village located in Slavonia, in the eastern part of Đakovština region.
The school in Semeljci was opened in 1786, and had many difficulties afterwards. Josip Zdravec was the first teacher in Semeljci. The original school building had wooden construction, a single clasroom, two teacher cabinets and a kitchen. The subjects taught were Illyrian and German language. The second school edifice was hastily built in 1833 with small funding. Boys were the only attendants of the school in 1875. The school grew from a two-grade schoool to a full four-grade public school.
The old building was demolished in May 1895, and in October of the same year, a new Municipal Public School was opened. It had 240 students. A regular eight-year school was allowed to open in the 1951-52 school year. In the 1959-60 school year, all of the separate grade schools were combined into a single central Primary School. It gained its full name of Josip Kozarac Primary School in Semeljci in September of 1960. Students from grades 1-4 went to local schools; after the completion of the fourth grade, they would continue with their education in the main school in Semeljci. Excavation for the foundations of the new school building began in October 1974, and the opening was on December 21, 1975. It was a two-story* building with 12 specialised classrooms, a workshop for technical education, a reading room, a kitchen with a dining room, a gymnasium, and recreation courts.
Josip Kozarac Primary School in Semeljci is a main school which still consists of five local schools in Kešinci, Vrbica, Forkuševci, Vučevci, and Mrzović. The Semeljci school has 450 students and 50 educational employees as of today.
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Master's degree - JOSIP JURAJ STROSSMAYER UNIVERSITY OF OSIJEK
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Years of experience: 13. Registered at ProZ.com: Nov 2013.