https://www.proz.com/kudoz/english/medical-general/2738767-lapp.html
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drew almost to replied to
"Test your English - free"
Jul 30, 2008 10:03
15 yrs ago
27 viewers *
English term

Lapp

English Medical Medical (general) enzyme terminology
There is an omnipresent term "Lapp lactase deficiency" in many summaries of product characteristics or other documents about medicinal products. I was asked a question what this Lapp referred to. I could not find any information in dictionaries or books. Probably it has something to do with Laponian people. When translated into Polish it is frequently considered a proper name (surname of the discoverer), and because it is so frequently repeated, nobody pays attention to this any more, and probably it is wrong. There is only one link in Google saying that it is a form of a rare congenital lactase deficiency. Have you any reliable information explaining the actual meaning of that word?
Responses
4 +4 people from Lapland

Discussion

Demi Ebrite Jul 30, 2008:
So, tracking back to mtDNA viariant studies . . . here's a great nightstand article for some enjoyable reading (!): http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=19...
Demi Ebrite Jul 30, 2008:
From a 360 viewpoint, a mention: "To ascertain, for example, whether an African or Lapp mtDNA variant, rather than nuclear DNA, affects coupling, mitochondria from Africans and Lapps could be placed separately into cells with identical nuclei. "
Demi Ebrite Jul 30, 2008:
I do think it's right - even though I can't substantiate it, because there are test study criteria excluding persons who have it for test subjects, and numerous drug interaction warnings naming 'Lapp lactase deficiency' as a condition. How odd.

Responses

+4
14 mins
Selected

people from Lapland

is this your link?
http://209.85.135.104/search?q=cache:i4VuUdUbKU4J:www.inchr....

it explains the background to the problem quite well.



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Note added at 21 mins (2008-07-30 10:24:38 GMT)
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some more info here:

http://www.google.it/search?hl=it&client=firefox-a&rls=org.m...

http://www.google.it/search?hl=it&client=firefox-a&rls=org.m...
Note from asker:
actually this is the one: http://www.cambridge.org/us/books/kiple/lactose.htm , thank you very much for the Russian publication. I only wonder why all SPCs replicate this phrase were not referring to Lapland populations. They should say congenital lactase deficiency instead. maybe in this case it is similar as in the case of the Finnish type nephrotic syndrome (a proper name).
Peer comment(s):
agree Tania McConaghy
52 mins
thanks.
agree Demi Ebrite : 'Lapp lactase deficiency', a rare, specific affliction, serious enough for interaction warnings. I guess if you REALLY need to know, you can read up on LAPP mtDNA ~ :>
6 hrs
thanks.
agree Veronica Prpic Uhing : Lapp lactase deficiency is the name for it as there are other types of the same
8 hrs
yes.
agree warren : exactly
11 hrs
thanks
neutral ElenaY : Could you please help me with the correct translation of term "Lapp lactase deficiency" into Russian?
141 days
i'm sorry Elena, I don't speak Russian.
Something went wrong...
4 KudoZ points awarded for this answer. Comment: "after reading the article I changed my mind. It is not a serious form of congenital lactase defficiency. It's a form of primary hypolactasia caused a polymorphism in a lactase gene typical for the people from Lapland. It is not more severe than other types of primary hypolactasia. nobody tests for it, probably such tests are even not available. repeating this phrase in drug documentation is pointless and should be abandoned in favour of the primary hypolactasia. Otherwise it will continue causing confusion. Thank you all for explanation."