Jun 16, 2005 16:09
18 yrs ago
1 viewer *
English term

Yamaguchi sarcoma or Yamaguchi virus?

English Medical Biology (-tech,-chem,micro-)
Does “Yamaguchi” relate to “sarcoma” or “virus”, i.e.:

1. Yamaguchi sarcoma
or
2. Yamaguchi virus?

I have the same problem with “Abelson” and “Gardner-Rasheed”.

CONTEXT
Activators of TRAIL-induced apoptosis

H.s. Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog (FGR), mRNA
H.s v-yes-1 Yamaguchi sarcoma viral related oncogene homolog (LYN), mRNA"""

Inhibitors of TRAIL-induced apoptosis

H.s v-abl Abelson murine leukemia viral oncogene homolog 2 (arg, Abelson-related gene) (ABL2), transcript

Responses

+1
13 mins
Selected

yamaguchi sarcoma

It's the sarcoma.

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Note added at 17 mins (2005-06-16 16:26:36 GMT)
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Similarly, Abelson murine leukemia: http://www.jimmunol.org/cgi/content/abstract/146/8/2805
Peer comment(s):

agree Anna Maria Augustine (X)
1 hr
neutral achisholm : but if they're talking about the transcript, they presumably mean from the viral genome, unless they are talking about transcripts isolated from the sarcoma (unlikely).
1 hr
The virus causing/associated with/first isolated from Yamaguchi sarcoma is the Yamaguchi sarcoma virus, but the answer to the asker's specific question is the one I give.
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4 KudoZ points awarded for this answer. Comment: "Thank you!"
3 hrs

>>>

"The YES oncogene is homologus to the gene of the Yamaguchi sarcoma virus. The product of the gene is associated with tyrosin- specific protein kinase activity and its amino acid sequence showv a high degree of homology with that of the SRC gene product of Rous sarcoma virus."
More at:www.hgmp.mrc.ac.uk/cgi-bin/wrapomin?164880
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