English term (edited): breakthrough

http://www.medscape.com/viewarticle/713174_2
Definition of Relapse and Nonresponse
Relapse and nonresponse are defined on the basis of the virological response to treatment (Fig. 1). A patient is said to have experienced a virological relapse if HCV RNA decreases and remains below the limit of detection (<50 IU/mL) during treatment but becomes detectable after cessation of treatment. If HCV RNA rebounds and becomes detectable in such a patient before treatment is completed, this is referred to as virological breakthrough. Virological nonresponse is evident when the serum HCV RNA level remains above the limit of detection throughout treatment and is formally defined as less than 2 log10 decline in HCV RNA between baseline and week 12. A patient who has less than 1 log10 reduction in serum HCV RNA at week 12 of treatment is said to have had a null response.


http://www.mednet.gr/archives/2009-3/pdf/295.pdf
Σε ασθενείς που λαμβάνουν αγωγή με νουκλεοσιδικά-νουκλεοτιδικά ανάλογα θα πρέπει να παρακολουθούνται τα επίπεδα της ιαιμίας τακτικά για να εντοπίζεται έγκαιρα η ιολογική διαφυγή.
Routine on-treatment monitoring of HBV DNA levels is imperative for detecting virologic breakthrough as early as possible

Κοίτα και αυτό (δυστυχώς δεν γίνεται να το αντιγράψω εδώ)
http://www.keelpno.gr/Portals/0/Αρχεία/Ηπατίτιδες/Ηπατίτιδα Β/HBV_Κατευθυντήριες Οδηγίες_Φεβ-2013.pdf