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growth hormone secretagogue type 1a receptor

Russian translation: рецептор стимулятора секреции гормона роста 1а типа

16:35 Apr 28, 2015
English to Russian translations [PRO]
Medical - Medical: Pharmaceuticals
English term or phrase: growth hormone secretagogue type 1a receptor
In the stomach, the ghrelin precursor (prepro‐ghrelin) is cleaved into proghrelin, which is further cleaved to produce ghrelin, a 28‐amino acid peptide termed desacyl ghrelin; desacyl ghrelin is acetylated by the enzyme MBOAT4 [membrane bound O‐acyltransferase domain containing 4, also known as GOAT (ghrelin O‐acyltransferase)] (Gutierrez et al.
2008; Yang et al. 2008) and becomes ‘active ghrelin’ with a high affinity to GHSR1a (**growth hormone secretagogue type 1a receptor**) (Kojima et al. 1999).


Active ghrelin is inactivated by the enzyme BCHE (butyrylcholinesterase) (De et al.
2004).
Active ghrelin produced in the stomach is released into the blood circulation, and it stimulates appetite in part by its actions on NPY/AgRP (neuropeptide Y/Agouti‐related peptide) expressing neurons in the ARC (Kojima and Kangawa 2010).
Maxim Polukhin
Local time: 15:19
Russian translation:рецептор стимулятора секреции гормона роста 1а типа
Explanation:
или рецептор, усиливающий секрецию гормона роста
Рецепторы грелина экспрессируются нейронами в дугообразном ядре и вентромедиальном гипоталамусе. Рецептор грелина — связанный с G-белком рецептор (GPCR), прежде известный как рецептор GHS (рецептор стимулятора секреции гормона роста)......
Selected response from:

NataliiaK
Ukraine
Local time: 15:19
Grading comment
Спасибо!
4 KudoZ points were awarded for this answer



Summary of answers provided
4рецептор секретагогов гормона роста типа 1a
GhostLibrarian
4рецептор стимулятора секреции гормона роста 1а типа
NataliiaK


  

Answers


2 mins   confidence: Answerer confidence 4/5Answerer confidence 4/5
рецептор секретагогов гормона роста типа 1a


Explanation:
...

GhostLibrarian
Russian Federation
Local time: 14:19
Works in field
Native speaker of: Native in RussianRussian
PRO pts in category: 608
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1 day 2 hrs   confidence: Answerer confidence 4/5Answerer confidence 4/5
рецептор стимулятора секреции гормона роста 1а типа


Explanation:
или рецептор, усиливающий секрецию гормона роста
Рецепторы грелина экспрессируются нейронами в дугообразном ядре и вентромедиальном гипоталамусе. Рецептор грелина — связанный с G-белком рецептор (GPCR), прежде известный как рецептор GHS (рецептор стимулятора секреции гормона роста)......


NataliiaK
Ukraine
Local time: 15:19
Specializes in field
Native speaker of: Native in UkrainianUkrainian, Native in RussianRussian
PRO pts in category: 48
Grading comment
Спасибо!
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