English to Russian Medical Other

Контекст:

Parasitological efficacy and effects on malaria-associated anaemia were evaluated in 250 malarious children aged two years and under, and efficacy was evaluated in 603 malarious children older than two but younger than five years of age following treatment with artesunate-amodiaquine (AA) or artemether-lumefantrine (AL). Kinetics of the disposition of parasitaemia following treatment were evaluated using a non-compartment model. Late-appearing anaemia (LAA) was diagnosed using the following criteria: clearance of parasitaemia, fever and other symptoms occurring within seven days of starting treatment, adequate clinical and parasitological response on days 28–42, haematocrit (HCT) ≥ 30% at one and/or two weeks, a fall in HCT to < 30% occurring at 3–6 weeks, absence of concomitant illness at 1–6 weeks, and absence of asexual parasitaemia detected using both microscopy and polymerase chain reaction (PCR) at 1–6 weeks.