English to Russian Medical Medical: Pharmaceuticals

The QTc analysis (Group 1) was based on a non inferiority hypothesis testing framework.

Approximately 40 palbociclib plus letrozole treated patients were needed to establish non inferiority (no unacceptable QTc prolongation from the palbociclib plus letrozole combination) between post baseline and baseline (ΔQTc) at all 5 QTc sampling time points on Cycle 1 Day 14 with 90% power.