Jan 19 11:52
4 mos ago
19 viewers *
Portuguese term
United Kingdom
35 years in the translation business
Native in: English 
Works in: Spanish to English, French to English, Italian to English, and 1 more.
substituição em sensibilidade relativa à referência
Portuguese to English
Medical
Medical: Pharmaceuticals
Prezista/ritonavir HIV drug
I am translating a booklet of information for healthcare professional relating to Prezista, a drug to treat HIV. This sentence is causing me problems in terms of the question posted above. "O fenótipo na linha de base de darunavir (substituição em sensibilidade relativa à referência) mostrou ser um fator preditivo de resultado virológico".
Proposed translations
(English)
| 5 +1 | shift in susceptibility relative to reference |
philgoddard
|
| 3 | reference-associated sensitivity substitution |
Ligia Fonseca
|
Proposed translations
40 mins
Ligia Fonseca
United Kingdom
United Kingdom
Native in Portuguese
Specializes in field
United Kingdom
Translator since 2003
Native in: Portuguese (Variant: Brazilian) 
Works in: English to Portuguese, Portuguese to English, Spanish to Portuguese, and 5 more.
reference-associated sensitivity substitution
It would be good to have more examples of where "referência" appears in the text - is the substitution associated to the reference or is the sensitivity related to the reference?
Note from asker:
| Sorry, no other instances of reference in the document. Also, I am not sure if sensibilidade means sensitivity (to the drug) or susceptibility, although I suppose they are the same thing, so it doesn't really matter in this case. |
+1
3 hrs
philgoddard
United States
United States
Native in English
United States
Six languages into flawless English
Native in: English
Works in: German to English, French to English, Spanish to English, and 4 more.
Related KudoZ points
:
2
shift in susceptibility relative to reference
You appear to be doing a back translation, so you just have to find the English product information. I don't know if your customer allows you to do this, but it does give you a definitive answer.
Baseline darunavir phenotype (shift in susceptibility relative to reference) was shown to be a predictive factor of virologic outcome.
http://www.google.com/url?q=https://ec.europa.eu/health/docu...
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Note added at 3 hrs (2024-01-19 15:37:48 GMT)
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Susceptibility means whether the virus is affected by the drug.
Baseline darunavir phenotype (shift in susceptibility relative to reference) was shown to be a predictive factor of virologic outcome.
http://www.google.com/url?q=https://ec.europa.eu/health/docu...
--------------------------------------------------
Note added at 3 hrs (2024-01-19 15:37:48 GMT)
--------------------------------------------------
Susceptibility means whether the virus is affected by the drug.
Note from asker:
| Naughty of them not to have told me it is a back-translation, but that would explain the rather suspect Portuguese :) I found some good reference material and have added a note and writtenthe correct English in a couple of places already. |
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