May 26, 2020 00:55
3 yrs ago
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English term
disease-modifying anti-rheumatic drug (DMARD)
COVID-19
GBK
English to Chinese
Medical
Medical (general)
Definition from
National Center for Biotechnology Info.:
Disease-modifying antirheumatic drugs (DMARDs) are a class of drugs indicated for the treatment of inflammatory arthritides including rheumatoid arthritis (RA), psoriatic arthritis (PsA), and ankylosing spondylitis (AS). They can also be used to in the treatment of other disorders including connective tissue disease such as systemic sclerosis (SSc), systemic lupus erythematosus (SLE), and Sjogren syndrome (SS), as well as in treatment of inflammatory myositis, vasculitis, uveitis, inflammatory bowel disease, and some types of cancers.
Example sentences:
Hydroxychloroquine has been available since 1955 as an antimalarial drug. I have at least 6 patients at the pharmacy who have used hydroxychloroquine to manage their rheumatoid arthritis, lupus, and Crohn disease. If you were sitting in my pharmacology class, I’d tell you that it is an antimalarial used as a disease-modifying antirheumatic drug (DMARD). I would tell you it is a cheap drug with good efficacy for some and also that it is 1 of 2 DMARDs that are safe to use in patients with liver failure. You would also learn that it may cause deposition of the drug in the melanin layer of the cones in the retina, underscoring the need for annual eye exams. (MJH Life Sciences)
DMARDs Not Linked to Poor Outcomes in SARS-CoV-2 RA Patients (Rheumatology Network)
The analysis of performance measures for rheumatoid arthritis (RA) care have allowed to identify gaps in care that include suboptimal use of disease-modifying anti-rheumatic drugs (DMARDs), according to a study published in Arthritis Care & Research. (Rheumatology Advisor)
Proposed translations
(Chinese)
| 5 | 改善病情抗风湿药 |
Yining Wang
|
Change log
May 23, 2020 00:29: changed "Kudoz queue" from "In queue" to "Public"
May 26, 2020 00:55: changed "Stage" from "Preparation" to "Submission"
May 29, 2020 01:57: changed "Stage" from "Submission" to "Selection"
Jun 5, 2020 01:54:
Jun 25, 2020 01:55:
Jul 25, 2020 01:57:
Proposed translations
120 days
Yining Wang
United States
United States
United States
Genetics, Nutrition and Medicine, M.S.
Native in: Chinese (Variants: Mandarin, Traditional, Simplified) 
, English (Variant: US)
Works in: English to Chinese, Chinese to English
改善病情抗风湿药
Definition from
中国免疫学杂志 2018, Vol. 34 I:
近年来随着对RA改变病情药物(disease—modifying antirheumatic drugsDMARDs)的不断认识和发展，特别是新型生物制剂在RA治疗中的应用，使对该病治疗的认识日新月异。美国风湿病学会在2002年RA治疗指南中就已经指出：在RA确诊3个月内应尽早给予DMARDs药物治疗，有助于延缓关节破坏¨]。目前大量研究也已经证实早期应用DMARDs不仅有助于控制症状，也对维持关节功能和结构有益。本文通过综述近年文献探讨RA治疗策略。
Example sentences:
“2020年6月，《Ann Rheum Dis》上的一项研究，对有关合成（s）和生物（b）类改善病情抗风湿药物（DMARD）安全性的进行了系统文献回顾（SLR），从而为2019年EULAR更新类风湿关节炎（RA）管理建议提供信息。” (环球医学资讯)
改善病情抗风湿药周期联合治疗类风湿关节炎疗效及临床意义研究 Curative Effects and Clinical Significance for Cycle Combination Treatment of DMARDs for Rheumatoid Arthritis ( 山西医科大学【网络出版年期)
Discussion
近年来，研究人员在阐明AD等神经退行性疾病的发病机制方面取得了很大进展。然而，这种基础研究的进展并没有转化为有效的缓解疾病（disease-modifying）治疗手段。
维基百科的相关解释：
Disease-modifying antirheumatic drug - Wikipedia https://en.wikipedia.org/wiki/Disease-modifying_antirheumati...
所以，我觉得DMARD可以翻译成“缓解疾病的抗风湿药”。仅供参考。