Glossary entry

Spanish term or phrase:

marcado (en este contexto)

English translation:

labeled

Added to glossary by Sherry Godfrey
Aug 6, 2006 21:06
17 yrs ago
21 viewers *
Spanish term

marcado

Spanish to English Medical Medical (general)
Los niveles plasmáticos de radioactividad en pacientes disminuyen en forma bifásica tras una dosis IV directa de cisplatino marcado.

I am not sure that it would be "marked" here....
Thanks!

Discussion

Alicia Casal Aug 6, 2006:
¿Cómo interpretas marcado?
Gracias

Proposed translations

+8
29 mins
Selected

labeled

Labeled cisplatin.
No conozco los mecanismos, pero se utilizan marcadores mediante isótopos radioactivos o por fluorescencia. Ver es en ref.

"The investigators, led by Dr. Michael Gottesman, administered fluorescently **labeled cisplatin** to both melanoma cells and control cells from a non-melanoma skin cancer line. The labeled drug was found in the cytoplasm of melanoma cells but not in the nuclei, where it would exert its cytotoxic effect. In contrast, the drug was found in both the cytoplasm and nuclei of control cells. In melanoma cells, cisplatin found near the plasma membrane colocalized with a melanosome marker, suggesting that it was trapped inside the organelles".

suerte.
Peer comment(s):

agree Paulo César Mendes MD, CT
3 mins
agree Rachel Fell
6 mins
agree Maria Paz Mella
12 mins
agree Roxanna Delgado
1 hr
gracias colectivas
agree Mónica Ameztoy de Andrada
2 hrs
agree Ana L Fazio-Kroll : Correcto.
6 hrs
agree Egmont
9 hrs
agree Dr Sue Levy (X)
10 hrs
Something went wrong...
4 KudoZ points awarded for this answer. Comment: "Gracias Claudia y todos!"
16 mins

along with a dye

A dye is often added to cisplatin injections.
Something went wrong...
35 mins

labelled

or "labeled" for US Eng.
I think
Usually it specifies the type of labelling but it seems to be a general term here

Evidence against a direct cytotoxic effect of alpha interferon and zidovudine in ... Wennerberg J: In vitro toxicity of Pt-191-labeled cisplatin to a human ...
www.co-oncology.com/pt/re/cooncology/fulltext.00001622-2001...

Alkylamine derivates of Ti (IV) coated porous silica beads ... Claeys, A. and De Moerloose, P. Microscale synthesis of N-13-labeled cisplatin. ...
www.radiofarmacie.ugent.be/pubradfarm.doc
Something went wrong...
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