English to German Medical Medical (general) Alzheimer-Forschung

Kontext: Künftige Bedeutung von Biomarkern für die Erforschung der Alzheimer-Krankheit
The effort to develop diagnostic and prognostic biomarkers has enormous implications for our nomenclature and future clinical practices. When the 1998 NIA consensus conference met to define the ideal characteristics of a diagnostic marker, they cited ease of use, simplicity and low cost as three practical considerations.12 As a result, brain biopsy is not likely to be considered noninvasive, simple to perform or inexpensive in the near future. However, if it were proven that a certain level of -amyloid deposition in the ***temporal cortex*** of a normal on biopsy was highly associated with AD in 2-3 years or if early intervention with a (yet-to-be-determined) -amyloid prevention agent resulted in a significant delay or prevention of AD, then even the brain biopsy procedure would take on a new light. For now, the science of biomarkers still has room to grow before it significantly alters the diagnostic nomenclature for dementia, and preventative medications are still a dream of the future, but the day of biomarkers in the diagnosis and treatment of AD is rapidly approaching.