placas
English translation: plaques
| 10:53 Mar 18, 2019 |
| Spanish to English translations [PRO] Medical - Medical (general) / Prostate biopsy | |||||||
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|  Selected response from: David Brown Spain Local time: 10:50 | ||||||
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| Summary of answers provided | ||||
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| 4 | plaques |
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| Terminology for prostate cancer histology based on Gleason score |
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| Discussion entries: 7 | |
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Answers
3 days 6 hrs confidence: 
plaques Explanation: See http://juanbarciapathology.blogspot.com/2015/03/pleural-cyto... plaques are major components of the luminal surface of superficial cells in mammalian urinary bladder. Asymmetric-unit-membrane (AUM) plaques are major components of the luminal surface of superficial cells in mammalian urinary bladder. ... Similar plaque clusters are present on apposing surfaces of cell pairs within the epithelium. Intraepithelial asymmetric-unit-membrane plaques in mammalian ... https://www.ncbi.nlm.nih.gov/pubmed/7425306 |
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Reference comments
6 hrs |
| Reference Reference information: Gleason 4 Gleason pattern 4 glands are no longer single/separated glands like those seen in pattern 1-3. They look fused together, difficult to distinguish, with rare lumen formation vs Gleason 1-3 which usually all have open lumens (spaces) within the glands, or they can be cribriform-(resembling the cribriform plate/similar to a sieve. An item with many perforations). Fused glands are chains, nests, or groups of glands that are no longer entirely separated by stroma-(connective tissue that normally separates individual glands in this case). Fused glands contain occasional stroma giving the appearance of "partial" separation of the glands. Due to this partial separation, fused glands sometimes have a scalloped (think looking at a slice of bread with bite taken out of it) appearance at their edges.[2][5] Gleason 5 Neoplasms have no glandular differentiation (thus not resembling normal prostate tissue at all). It is composed of sheets (groups of cells almost planar in appearance (like the top of a box), solid cords (group of cells in a rope like fashion running through other tissue/cell patterns seen), or individual cells. You should not see round glands with lumenal spaces that can be seen in the other types that resemble more the normal prostate gland appearance. https://en.wikipedia.org/wiki/Gleason_grading_system#Gleason... -Patrón 5: Carcinoma indiferenciado con escasa o nula diferenciación glandular formando placas sólidas o un crecimiento difuso (imagen 5). https://zaguan.unizar.es/record/47453/files/TAZ-TFM-2015-141... |
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1 day 7 hrs |
| Reference: Terminology for prostate cancer histology based on Gleason score Reference information: From Left to Right [Images see reference link]: 1st Row: Closely packed uniform sized and shaped large glands; Large variably sized and shaped glands, some with infolding; Uniform medium sized glands; Variably sized glands 2nd Row: Occasional tangentially sectioned glands amongst well-formed small glands; Occasional tangentially sectioned glands amongst well-formed glands with open lumina; Back-to-back discrete glands; Branching glands 3rd Row: Large irregular cribriform glands with well-formed lumina; Irregular cribriform glands with slit-like lumina, glomeruloid structures, and fused glands; Irregular cribriform glands with small round lumina; Small round cribriform glands 4th Row: Poorly-formed glands with peripherally arranged nuclei; Small poorly-formed glands; Small poorly-formed glands; Fused poorly-formed glands 5th Row: Sheets of cancer; Sheets of cancer with rosette formation; Small nests and cords of tumor with scattered clear vacuoles; Individual cells 6th Row: Nests and cords of cells with only vague attempt at lumina formation; Solid nests of cancer; Solid nests with comedonecrosis; Cribriform glands with central comedonecrosis. http://pathology.jhu.edu/prostatecancer/NewGradingSystem.pdf |
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